Explore and ask

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Reading DNA base by base · explore and ask

See the model read a disease element, and ask about what you see

Answers by Claude, grounded in the Kircher 2019 assay, AlphaGenome zero-shot predictions, and both source papers.

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Spearman vs measured

Measured effect (Kircher MPRA)

ACGT

Predicted DNASE, from DNA alone

ACGT
silencing activating clinically significant click a base to ask about it →

Clinically significant variants here

    None annotated in this element.

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